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Scientists identify people most likely to benefit from statins

This article tells the study that investigate which profiles are best suited for treatment with stanines.

The recommendation to "The American Heart Association 2013" about the use of stanines and about how much is prescribed. Researchers at the University of Washington have found that studying genetics can know that people can benefit from therapy against cholesterol.

In a study published in the journal "The Lancet" carried by scientists they was investigated the risk of heart attack among nearly 50,000 people . Sex, age, cholesterol levels, smoking and diabetes precedent to designate the group of individuals into account.

“There is ongoing debate over which individuals should be allocated statin therapy to prevent a first heart attack,” study author Nathan O. Stitziel, a Washington University cardiologist and human geneticist. “Genetics appears to be one way to identify high-risk patients.” Stitzel say that more research is needed to confirm the results.

“Regardless, we can at least say that patients with a high genetic-risk score appear to benefit more from statin therapy because they’re starting at a higher baseline risk, even controlling for all the clinical measures we routinely examine.”

The study authors analyzed 27 components of the DNA of each individual to calculate their genetic risk. They claim that these 27 components are related to coronary heart disease.

The American Heart Association and the American College of Cardiology said in 2013 that statins could be prescribed to an estimated 33 million Americans without heart disease who have at least a 7.5 percent risk for heart attack or stroke within the next 10 years.